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In addition, a total of 9.3 million lives could potentially be saved among those who quit smoking before the age of 65.

95% CI: 1.051.25) (Table 5)

This model relies on resource regeneration and the phasing out of single-use products, particularly those containing hazardous substances

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22 In addition, deubiquitinating enzymes (DUBs) regulate mitophagy by deubiquitinating Parkin or its targets on the mitochondrial, and Parkin can mediate nuclear translocation of transcript factor EB (TFEB), thereby upregulating the expression of genes associated with lysosome biogenesis (Fig