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More independent research on the topic, not funded by the tobacco industry, is also needed, the review states

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Compared with traditional meta-analysis using linear mixed effect models, MR-BRT relaxes the assumption of a log(linear) relationship between exposure and risk, incorporates between-study heterogeneity into the uncertainty of risk estimates, handles estimates reported across different exposure categories, automatically identifies and trims outliers, and systematically tests and adjusts for bias due to study designs and characteristics

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Here are some great hobbies or interests to pursue: [9] Do something with your hands