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As with all fluoroquinolones, use CIPRO with caution in epileptic patients and patients with known or suspected CNS disorders that may predispose to seizures or lower the seizure threshold (for example, severe cerebral arteriosclerosis, previous history of convulsion, reduced cerebral blood flow, altered brain structure, or stroke), or in the presence of other risk factors that may predispose to seizures or lower the seizure threshold (for example, certain drug therapy, renal dysfunction)

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The FDA or EPA should require e-cigarette manufacturers to develop standard e-cigarette waste management processes and clean-up programs that are safe and environmentally conscious and enact penalties for industry non-compliance