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Specifically, compared with corresponding adult counterparts who initiated before age 18, the number of moderate-severe SUDs was 32% lower among those initiating alcohol at ages 2129 (IDR = 0.68, 95% CI = 0.570.83), 21% lower among those initiating cannabis at ages 2129 (IDR = 0.79, 95% CI = 0.690.90), and 4562% lower (IDRs=0.380.55, 95% CIs=0.310.76) among adults who never initiated alcohol, cannabis, or nicotine use

Finally, some antidepressants may have a specific effect on neural pathways (e Ahluwalia JS, Harris KJ, Catley D, Okuyemi KS, Mayo MS

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Practice stress management techniques: Smoking often becomes a coping mechanism for stress

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