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Chemical Irritation : Cigarette smoke contains over 7,000 chemicals, many of which irritate the throat lining, causing inflammation, swelling, and redness

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Moreover, in human small airway epithelial cell lines (HSAEpiCs), uPA and uPAR inhibition can block CSE-induced EMT by reversing the expression of E-cadherin and -catenin and delaying the induction of N-cadherin and Vimentin [174, 175]

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Griera writer, bartender, and cocktail consultant who enjoys the occasional cigar and pipe but says humanity would have been far better off if the mass-produced cigarette had never been inventedis by no means calling for a return to the situation that Gouin found intolerable