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Ethical approval for all experimental procedures was granted by the Zhejiang University Medical Laboratory Animal Care and Use Committee and the Ethics Committee for Animal Studies at Zhejiang University

Prior visit cigarette packs are collected

A variation of the kretek is sold: "cigars" that are similar in size and shape to the original kreteks, also with a filter and the original tobacco/clove blend, but in a tobacco-based paper

Suppressed immune system: People may have weakened or suppressed immune systems due to HIV, immunosuppressant drugs, or other factors

The extent to which VO2max is reduced depends on the amount of CO that smokers inhale