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doi: 10.3390/ijerph17072610, Summary Keywords burden, drug use, epidemiology, Global Burden of Disease Study, high alcohol use, substance use, tobacco Citation Zheng W, Qin R, Liu M, Yang K, Li J, Liu S, Wang T and Gao X (2026) Burden of disease attributable to tobacco, high alcohol use, and drug use from 1990 to 2021