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The tests can tell us lots of sorts of information all at once, like the safety if a drug across lots of different internal organs, how the drug travels around the body and other information that helps us to design much safer human trials

Liggett faced pressure from other companies not to go ahead as the implication would be that all other cigarettes were unsafe

P., Kuo, B

The first nationally representative study of smoking hazards in China

At present, there are no other data comparing nicotine pharmacokinetics between cigarettes and this relatively new product category of NPs, but previous studies have similarly reported greater AUC and C max values for some types of snus than for cigarettes [25,26,27], probably due to the longer period of snus use relative to smoking a single cigarette