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The observed mtDNA gene upregulation reached significance at 5% CSE (10 weeks for MT-CYB , MT-CO2 and MT-RNR1 ), and at 6% CSE (12 weeks for MT-CYB and MT-CO2 ), but not at the early point with 3.5% CSE (4 weeks)

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*Each measures 4.5" tall x 3" wide x .5" on the larger, and 3" tall x 2.25" wide x 1.25" on the "mustard" colored one and 3" tall x 3" wide x 1" thick on the Blue Bugler

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18 For the final rule, see Tobacco Products