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CLCA4 encodes a channel involved in chloride transport into epithelial cells [24], while CRCT1 encodes the cysteine rich C-terminal 1 protein that may be involved in keratinocyte differentiation [25], yet little is known regarding the expression of CLCA4 and CRCT1 in COPD and their involvement in inflammatory pathways

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Unfortunately, the devices have a wide appeal of their own, particularly amongst teens and young adults, and many people who have never smoked cigarettes take up the vaping habit

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