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Modulation of pulmonary immune function by inhaled cannabis products and consequences for lung disease

Hatcher JL, Sterba KR, Tooze JA, Day TA, Carpenter MJ, Alberg AJ, et al

BMJ Group: 101102

A condensed, highly toxic irritating gas High toxicity upon inhalation Used in the chemical industry to produce plastics and insecticides In contact with air, it forms a white cloud Smells like freshly cut hay Low solubility causes symptoms in the lower airways rather than the upper airways Toxic pulmonary edema may occur after a latent period of 24-48 hours Patients should be monitored for 48 hours Treatment After Phosgene Injury Treatment similar to other irritating gases Bronchodilators and corticosteroids via inhalation should be administered liberally If ARDS develops in the lungs, pulmonary hypertension progresses rapidly Significantly increased pulmonary vascular resistance (PVR) Treat with Nitric Oxide (NO), prostacyclin (epoprostenol Flolan), or bosentan (Tracleer) Phosphine (PH) Phosphine is a colorless, flammable, and highly toxic gas with a smell resembling garlic or decaying fish

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