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All other authors declare that they have no competing interests

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Cigalikes A Cigalike device is an e-cigarette thats designed to look and feel like a traditional cigarette

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Abbreviations COPD: chronic obstructive pulmonary diseases CS: cigarette smoke BALF: bronchoalveolar lavage fluid CF: cystic fibrosis CFTR: cystic fibrosis transmembrane conductance regulator CD: Crohns disease UC: ulcerative colitis MS: multiple sclerosis RA: rheumatoid arthritis SLE: systemic lupus erythematous References DeMarini DM