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Following body temperature assessment, each animal was placed in the center of the field and distance traveled and velocity were recorded during a 10-min observation period and analyzed using Noldus Ethovision XT software

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The authors determined that nicotine did not cause cytotoxicity, that some products were noncytotoxic to pulmonary fibroblasts but cytotoxic to both types of stem cells, and that cytotoxicity was related to the concentration and number of flavorings used