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Tobacco-specific nitrosamines (TSNAs) such as N-nitrosonornicotine (NNN) and 4-(methylnitrosoamino)-1-(3-pyridyl)-1-butanone (NNK) have been previously characterized in the vapors of e-cigarettes [35]

Several detrimental consequences of chronic exposure have been reported, including ocular surface malignancies, alteration in tear film stability and quality, tear production and corneal epithelial thickness, loss of upper and lower eyelid meibomian glands, and dry eye symptoms or ocular irritation

Smoking is one of the leading causes of preventable diseases worldwide, including lung cancer, chronic obstructive pulmonary disease (COPD), and cardiovascular diseases

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