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A recent paper, reporting on telomerase-deficient mice, showed that telomere dysfunction induced a profound p53-dependent repression of the master regulators of mitochondrial biogenesis and respiration, PGC-1 and PGC-1, which led to a bioenergetic compromise due to impaired oxidative phosphorylation and ATP generation 34

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Perchloroethylene (CCl) Perchloroethylene, also known as tetrachloroethylene, is a colorless liquid with a sweet odor, primarily used in dry cleaning and metal degreasing processes