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There are as many as 28 different carcinogens in chewing tobacco

Erythroplakia is usually a red patch with a granular velvet-like surface and will have well-circumscribed clinical margins

The chewed tobacco products are betel quid with tobacco (Mainpuri and others) and pan masala with zarda and gutkha

Lashkar in Guwahati shared that pan masala and zarda are the best-selling items in his shop, with daily sales averaging one bundle of pan masala and two bundles of nicotine-laced tobacco

Specifically, nicotine and its primary metabolite cotinine are metabolized by the uridine 5-diphospho-glucuronosyltransferase (UGT) superfamily enzymes: specifically UGT2B10 for nicotine and cotinine, and UGT2B7, UGT2B15, and UGT2B17 are responsible for metabolizing androgens