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There is some evidence to suggest that an increase in receptor expression may be involved in the development of cough hypersensitivity, as evidenced by an increase in TRPV1 expression in the lungs of chronic coughers compared to healthy controls (Groneberg et al., 2004)

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May 30, 2026 Every year on May 31, World No Tobacco Day highlights the health risks associated with tobacco use and advocates for effective policies to reduce tobacco consumption

the researchers described this as a significant increase