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The exclusion of older individuals (aged above 65 years) restricts understanding of the effects of SLT on older populations, where multiple health issues and accumulated tobacco exposure might increase periodontal damage

Smoking-associated squamous metaplasia in olfactory mucosa of patients with chronic rhinosinusitis

CSE increased EZH2 and reduced DAB2IP expression in 16HBE cells The chronic stimulation of 16HBE cells with CSE (10 and 20%) induced an overexpression of EZH2 after 7, and 14 days of treatment, and conversely a downregulation of DAB2IP, as shown by the selected representative western blot images (Fig