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Smoking has been shown to induce shifts in the microbiota across several body niches, including the oral cavity, respiratory tract, and gastrointestinal system

Gilbert syndrome Gilbert syndrome is a genetic liver disease characterized by high bilirubin levels, mild jaundice, and yellow stools

The main risk of long-term use is a continued dependence on nicotine, but since nicotine gum lacks the harmful chemicals found in cigarettes, the risks are significantly lower

However, the increase was not attributable to oral cavity, esophagus, stomach, colorectal or pancreas cancers

HCC (hepatocellular carcinoma), cancer of the testes