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Trapped between nicotine's two-hour elimination half-life and a gradually escalating need to smoke harder or more, the dependent smoker faces five primary recovery hurdles: (1) appreciation for where they now find themselves, (2) reclaiming their hijacked dopamine pathways, (3) breaking and extinguishing smoking cues, (4) abandoning smoking rationalizations, and (5) relapse prevention

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Even if the patient wants to try e-cigs as a cessation aid, the physician must inform the patient that no data are supportive of the effectiveness of e-cigarettes as smoking cessation aids

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