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Application of toxicological risk assessment principles to the chemical constituents of cigarette smoke

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If HIV exposure is a separate concern, for instance after unprotected sex with a partner of unknown HIV status, a fourth-generation antigen-antibody test is the appropriate next step, reliable from approximately 18 to 45 days post-exposure per CDC guidance

Among these are heart attack, heart failure, peripheral vascular disease, and stroke, all of which can be directly linked to tobacco use