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In the time of histological study of striae of this pa- tient, which was taken before the procedure of treatment by APCPB, were noted an atrophy and thinning of epi- thelium, hy perkerat osis, fl atteni ng of papil lae and smoothing of papillary layer in dermis, and almost total absence of reticular layer which was re placed with connective tissue with a chaotic arrangement of fibers and a small amount of blood vessels with periva scular leukocytic infiltration with prevalence of lymphocytes and macrophages

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Although Benedict XIII (a snuff-taker himself) reinforced the necessity to keep tobacco away from the altar and the tabernacle, in 1725 he revoked the penalty of excommunication for smoking in St