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In this experiment, the phosphorylation levels of AMPK-ACC proteins in the CSC exposure group were significantly increased, while the expression levels of Hmgcr and CYP7A1 protein were significantly decreased, which suggested that CSC exposure was able to affect glucose and lipid metabolism by AMPK-ACC and CYP7A1 gene expression or phosphorylation

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Black packaging is associated with higher priced products, prestige and elegance.11 Black is commonly used by those in creative design to convey sophistication (eg, tuxedos and black clothing as a fashion statement), importance and respect (eg, limousines and official cars that transport dignitaries are commonly black) and appearing authoritative.12 13 Specific to cigarette packaging, internal documentation from Philip Morris indicates that shiny or textured black backgrounds communicate classy, contemporary, distinguished, stylish, rich, aspirational (important, competent, successful) attributes to consumers.14 Although the meaning of colours can vary cross-culturally, expensive, powerful and authority are meanings associated with black that transcend domestic markets, including several Asian cultures such as China, Japan and South Korea.15 Intrafamily codes continue to be used to infer relative harm for PMIs new brand architecture that includes Marlboro brand variants being offered in black-coloured cigarette packages

The evidence that standardised packaging will change actual smoking behaviour is less clear, as this kind of research is difficult to do, but it is expected that as a result of these changes in attitudes and beliefs, standardised packaging will encourage some smokers to think twice about their smoking behaviour and, crucially, discourage some of the 200,000 children who start smoking every year from taking up the habit