Over time, the brain becomes less sensitive to dopamine, requiring more nicotine to achieve the same effects, a process known as tolerance
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At the very least, they should stop selling kid-friendly e-cigarette flavors. Tobacco use among young people is increasing in the U.S., driven in large part by increasing use of e-cigarettes, according to a report released in February by the Centers for Disease Control and Prevention
[DOI] [PMC free article] [PubMed] [Google Scholar] 109.Strulovici-Barel Y, Shaykhiev R, Salit J, Deeb RS, Krause A, Kaner RJ, et al