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In the microfluidic small airway-on-a-chip, one hollow microchannel is lined by living human bronchiolar epithelium, obtained from COPD patients or healthy people, which is exposed to air delivered under normal breathing motions by the smoking instrument

Another assessment found that in a separate survey group, the proportion of people who used cigarettes in addition to ZYN decreased from 42 percent to 15 percent over a median time of five to six months

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The researchers further showed that the two molecules were able to modify weight even in a nonsmoking setting