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This creates strong cravings and withdrawal symptoms when tobacco use stops

Typically, the disease emerges in adolescents or young adults (239)

[15][22] Emergency responses for nicotine overdose Call 911 or the American Association of Poison Control Center at 1-800-222-1222 right away if any of the following symptoms occur : difficulty breathing, seizures or convulsions, loss of consciousness, irregular or slow heartbeat, severe vomiting or persistent nausea, confusion, dizziness, or altered mental state, excessive salivation (drooling) or sweating

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Acetaldehyde, a component of cigarette smoke and metabolic product of alcohol breakdown, has epigenetic and genetic toxic effects (Shukla and Lim, 2013) and can inhibit key mitochondrial reactions and functions ( High levels of these reactive aldehydes form adducts on macromolecules present in the lungs, leading to an inflammatory response