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32400574 to X.L.), the National Key R&D Program of China (2021YFF0702000 to C.D.), the National Science and Technology Major Project (2023ZD0506800 to C.D.), th e 1.3.5 Project for Disciplines of Excellence, West China Hospital, Sichuan University (ZYYC21011 to C.D.), the National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University (Z2023JC003 to C.D.), the Science and Technology Department of Sichuan Province (2022YFH0116 to C.D.), the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD to C.D.), the China Postdoctoral Science Foundation (2024M752193 to H.D.C

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