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Known neurotoxic substances include nicotine and cotinine, its main metabolite 14,15

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Richard Bonnie, a University of Virginia professor of health and law who headed the analysis, previously told me that delaying when people start smoking is crucial because older people perhaps more aware of their mortality and the health effects of tobacco are less likely to initiate smoking

This can lead to cracked wrappers, a loss of flavor, and a diminished smoking experience

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