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For current smokers (about 1 billion people globally), the best single step they can take to reduce their risk of harm is to quit tobacco and nicotine use altogether

Those with higher nicotine tolerance may opt for strengths up to 24 mg/mL for a more satisfying experience

"There is growing concern that flavorings such as grape and cherry, and others with appealing names including brownie and gummy bear, now found in many small cigars, hookah tobacco and e-cigarettes, can entice youth to try these products and potentially lead to a life-long, deadly addiction."

The risk of stroke, 41%