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It then goes on to inform us that 'and possibly she may - for the amazing strides of medical science have added years to life expectancy' You can 'thank your doctor and thousands like him - toiling ceaselessly - that you and yours may enjoy a longer better life'

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This makes it difficult for the organs and soft tissues of the body including those in the mouth to receive nutrients, as well as oxygen

doi:10.1111/add.13506 6

Discussion Understanding how nicotine affects decision-making has been challenging, because two different physiological aspects need to be distinguished 41 : (i) nicotine as a reinforcer that directly activates the dopaminergic system to produce reinforcement and nicotine-seeking, and (ii) nicotine as a neuromodulator that alters nicotine-independent decision-making processes by modifying the dynamics and computational properties of cholinoceptive circuits