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29 Until more conclusive studies can be conducted, some countries, including Brazil, Canada, Uruguay, Singapore, and Turkey, have barred ENDS

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Among the 2,120 patients with CD whose data were complete, the HRs for ever smoking, previous smoking, and current smoking were 1.2719 (95% CI: 1.16361.3903, p = 1.19e-7), 1.2655 (95% CI: 1.15541.3869, p = 3.98e-7) and 1.3707 (95% CI: 1.21141.5509, p = 5.62e-07), respectively, greater than those of never smokers