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Oakland (CA): Air Toxicology and Epidemiology Branch, Office of Environmental Health Hazard Assessment, California Environmental Protection Agency

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5.1 Focus on Smokers with CV Disease Several meta-analyses showed that both varenicline and combination NRT are more effective than bupropion or single NRT in smokers suffering from a chronic CV disease [4], making the first two approaches the first-line therapies for smoking cessation in patients with a history of CV disease (see Table 3)

The country in the EU with the fewest smokers is Sweden, where just 9 percent of adults smoke, and the country with the highest number of smokers is Bulgaria, where 28 percent of adults enjoy a cigarette