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Germany and Finland were the main financers of the development program, with Switzerland providing resources directly to the GGC

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MtDNA methylation determination For mtDNA methylation measurements, mtDNA isolated from the TRIzol RNA phase [44] was digested by HindIII (Thermo Scientific, USA), with cutting sites located in MT-CO1 , MT-ND4 and MT-ND5 , which are outside the assessed DNA regions (Suppl