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This estimate includes 491 male deaths and 395 female deaths, 82 deaths at age 25-44 years, 441 deaths at age 45-64 years, and 361 deaths at age 65 years and over

References Ernst & Young

Primary review of the observational literature yielded several studies showing a positive association between e-cigaretteever use and past 30-day smoking status, which is a weak proxy for patterns of smoking indicative of progression in frequency and intensity

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