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Reduced immunity and increased risk of severe attacks : Smoking impairs the lungs capacity to combat infections, which can result in more frequent asthma attacks and raise the risk of severe, potentially fatal episodes

Cigarette smoke is associated with up-regulation of inducible NOS and COX-2 protein expression and activity in granulosa cells of women undergoing in vitro fertilization

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The play follows the lives of two best friends, Jack Worthing and Algernon Moncrieff