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The actual cinching is more of an almond or an eye-shaped shank than it is maybe a D but with that half saddle, there's more negative space, so the eye follows the lines of the pipe a little better

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5.3 Therapeutic targeting of mitochondrial dynamics Similar to how fusion can be manipulated to enhance bioenergetic function, fission can also be manipulated in a way that changes the overall function of the mitochondria