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Data compiled by the Department of Defense indicates smokeless tobacco is used by approximately one-fifth of 18- to 24-year-old military males which is twice the national average despite that fact that chewing tobacco is not a safe alternative to smoking

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Prolonged use has also been associated with metabolic issues such as insulin resistance, which can heighten cardiovascular risks

Association of time since smoking cessation and since the last depressive episode The mean time since smoking cessation was 17.0 years (SD = 12.2), while the mean time since the last depressive episode was 6.3 years (SD = 8.2)