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Patch national staffer Dan Hampton contributed to this report

24 However, it is limited in its application by its potential side effects, including dry mouth, constipation, nausea, sedation and headaches, and a risk of arrhythmia in patients with cardiovascular disease

Effect of Nicotine on Intestinal Microbiota Nicotine, as the primary active substance of tobacco, is inhaled into the lungs and fast absorbed in the pulmonary alveoli and is also absorbed through the skin and gastrointestinal tract