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These models incorporate spatial and temporal smoothing and a series of county- and state-level covariates to improve predictions for all counties, including those with limited data available in a given year from the BRFSS

A transcriptomic analysis between primary oral and bronchial models following e-cigarette aerosol exposure showed that bronchial epithelium was more sensitive than oral tissue but recovered quicker suggesting a tissue-specific response through distinct molecular pathways [23]

Restrictions on advertising tobacco products and where individuals could smoke began to take effect