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Numerous in vivo and in vitro studies have shown that nanoparticles, across a very wide range of sizes, shapes, and compositions, cause pulmonary inflammation [69, 70]
Still, the agency left room for shifting the focus of its rules
Exclusive HTP users had modestly but significantly lower concentrations of HDL-C than never smokers, with the pooled mean difference being 1.1 (95% CI 1.5 to 0.6) mg/dL
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