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The fact that dual use - using both traditional, combustible cigarettes and e-cigarettes - had similar cardiovascular disease risk to smoking cigarettes only is an important finding as many Americans are taking up e-cigarettes in an attempt to reduce smoking for what they perceive is a lower risk, said Andrew C

Gottlieb called for additional steps to prevent the marketing of e-cigarettes directly to kids and prevent online sales to minors

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None of the mechanistic studies they refer to have been validated as actual risk indicators in humans, and the authors inability to recognise that leads to misleading conclusions." writes Peter Shields

The error estimates are my best guesses after reading the sources and combining them with the arguments for over and underestimates above