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Amongst 1,053 people without frequent exacerbations , SUNSET (2018) compared continued triple therapy for up to 26 weeks (tiotropium 18 mcg/d + salmeterol 50 mcg / fluticasone 500 mcg twice/d) with abrupt discontinuation of ICS after long-term triple therapy , replaced by once daily LAMA/LABA (indacaterol 110 mcg / glycopyrronium 50 mcg)

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