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According to the Surgeon General, quitting smoking is the single most important step a smoker can take to improve the length and quality of his/her life

Regardless of how nicotine is absorbed, once this chemical enters the bloodstream, it circulates throughout the body and travels to the brain, where it crosses the blood-brain barrier

The research showed that nicotine exposure decreased electrically-stimulated dopamine release across various stimulation frequencies, and these changes in dopamine sensitivity predict individual variations in vulnerability to substance use disorders

Sharma, [email protected] These authors have contributed equally to this work and share first authorship This article was submitted to Microbiome in Health and Disease, a section of the journal Frontiers in Cellular and Infection Microbiology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers