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Future research to identify other susceptibility factors, such as genes that modify carcinogen metabolism or DNA repair, will need to be substantially larger and to quantify lifetime tobacco exposure with more precision than have past studies in order to distinguish gradations in risk due to exposure from those caused by genetic susceptibility
Manageable levels of DNA damage initiate DNA repair by PARP-1 mediated ADP-ribosylation of itself and associated proteins required for base-excision repair 20
Its a type of stimulant drug, in the same group as cocaine and ice (crystal methamphetamine)
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