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[100] The most common use of dogs is in the safety assessment of new medicines [101] for human or veterinary use as a second species following testing in rodents, in accordance with the regulations set out in the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use

Circumstantial evidence, I agree, but it all adds up to an almost unanswerable case

Effective medications include varenicline and bupropion

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