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Risk of Dependence and Addiction: The reinforcing effects of nicotine on the brains reward system lead to dependence and addiction, characterized by compulsive drug-seeking behavior despite negative consequences

Compared with placebo, the likelihood of quitting smoking was roughly doubled with NRT (1.84, 95% CI 1.711.99) and bupropion (1.82, 1.602.06) and was improved further with varenicline (2.88, 2.403.47) (Cahill et al., 2013)

Table: Varenicline (Chantix) Facts Click to view as full-sized PDF

OTC Some smoking cessation aids are available OTC, while others require a prescription

"We use ear, or auricular acupuncture, and have found that a total of six treatments increases quit rates by 30%." Give yourself a hand While most massages are whole-body, full-hour affairs, two minutes of self-message can have a powerful anti-smoking effect