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Things You Didn't Know About Big League Chew Chocolate cigars and bubble gum that mimicked chewing tobacco were some of the best and more innocent ways we got to pretend to be cool as kids (I'm kidding, stay off drugs, guys!)

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However, the large proportion of CFTR expression deriving from other epithelial cell types and our observation of FOXI1 / CFTR decoupling by time course and knockout electrophysiology cautions against the simple model where cystic fibrosis is caused by loss of CFTR function in FOXI1 + ionocytes

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