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Not only does nicotine stimulate dopamine release within ten seconds of a puff, suppression of MAO and normal dopamine clean-up allows it to linger far longer than a natural release, such as occurs when eating food or quenching thirst
In the early 1960s, nearly half of Swedish men smoked
The dosages applied in these investigations ranged from 400 to 3200 mg/d, and treatment length ranged from two to 30 days
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