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Although previous studies have reported a significant association with lung cancer based on case-control designs [13, 14], the relevance of combining these risk scores and smoking for individual subjects and whether smoking and genetic risk have a synergistic effect remains uncertain

20 NagataC.NakamuraK.FujiiK.KawachiT.TakatsukaN.ObaS.et al (2008)

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The study, published Wednesday in the Journal of the American Heart Association, found smokers were more likely than nonsmokers to have a heart attack or stroke in middle age with no prior indication they had cardiovascular disease sometimes with fatal consequences

Unlike other odours that can be aired out, smoke can really get deep into the fabric and surfaces of your car