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Prolonged exposure to nicotine and the numerous toxic chemicals present in tobacco smoke can damage the lungs, leading to chronic obstructive pulmonary disease (COPD) and an increased risk of respiratory infections

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In order to widen the knowledge on available literature and provide more comprehensive overview and support the broader objectives of the present review, some articles that did not meet the formal inclusion criteria - due to lack of open-access free full text (as per the PubMed text availability search filter) and/or not in English, and/or present in different databases - were nonetheless analyzed in a specific paragraph (see section Further relevant evidence on passive smoke and pets)

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